How do you follow up after sending a proposal?

I am curious to hear how sales professionals manage the period after sending a proposal to a prospect. How do you decide when to follow up, and what tells you that a prospect is still considering the proposal? Do you rely mainly on scheduled follow-ups and conversations, or do you also pay attention to how prospects interact with the proposal? I would love to hear how others handle this stage of the sales process and what has worked for them.